Can a AMD Instinct MI300X (192GB) run Gemma 3 27B?

Yes — Gemma 3 27B runs at FP16 (54.0 GB) at about 60–90 tok/s on a AMD Instinct MI300X (192GB).

How much memory does Gemma 3 27B need?

Gemma 3 27B needs about 12.1 GB at 4K context at its smallest quantization. A AMD Instinct MI300X (192GB) has 192.0 GB.

Yes — Gemma 3 27B runs on a AMD Instinct MI300X (192GB) at FP16

Yes — it runs great.

Runs great

Best fit: Gemma 3 27B at FP16 · 54.0 GB weights · 60–90 tok/s on a AMD Instinct MI300X (192GB).

Arena Text Overall · style-controlled

1,365FP16 untested

gemma-3-27b-it · published configuration reference · FP16 not tested

Arena Text Overall (style-controlled), exact published entry gemma-3-27b-it, 2026-10-08: reference rating 1,365.4. Published confidence bounds 1,361.7–1,369.1. 46,672 votes. Published gemma-3-27b-it configuration reference. Reasoning mode is not disclosed by the Arena dataset. Tested precision, runtime and sampling settings are not disclosed in this dataset. Selected FP16 has not been measured by this Arena entry. No quantization quality adjustment is applied.

Snapshot published 2026-10-08 · snapshot imported 2026-10-11 UTC · validated last-good data · manual refresh

Arena leaderboard dataset · Arena / lmarena-ai, Arena Leaderboard Dataset (CC BY 4.0). Selected Text Overall style-controlled rows; field names adapted, ratings unchanged. · dataset CC BY 4.0 · revision e16f90232986

Total memory at 4K context: 55.6 GB; Weights + KV cache + runtime overhead
Estimated generation: 60–90 tok/s
Estimated first token: ~1.3s

Every quantization on this machine

On small screens, each quant lists every metric below its name. On wider screens, scroll sideways for total memory, speed and fit. Keyboard: focus the table, then use the arrow keys. Quant names stay visible.

Gemma 3 27B quantizations on AMD Instinct MI300X (192GB), estimated at 4K context. Weights and total memory are shown separately.
Quant	Weights	Total memory	Speed	Fit
Q2_K	10.5 GB	12.1 GB	178–268 tok/s	Runs great
Q3_K_M	13.4 GB	15.0 GB	157–236 tok/s	Runs great
Q4_K_M	16.6 GB	18.1 GB	140–210 tok/s	Runs great
Q5_K_M	19.3 GB	20.8 GB	127–191 tok/s	Runs great
Q6_K	22.2 GB	23.7 GB	116–175 tok/s	Runs great
Q8_0	28.7 GB	30.3 GB	97–146 tok/s	Runs great
FP16	54.0 GB	55.6 GB	60–90 tok/s	Runs great

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