Can I run this LLM?
Can a AMD Instinct MI300X (192GB) run Gemma 4 26B-A4B (MoE)?
Gemma · Apache 2.0 · estimated for a 192.0 GB machine at 4K context.
Yes — it runs great.
Best fit: Gemma 4 26B-A4B (MoE) at FP16 · 50.5 GB · 192–287 tok/s on a AMD Instinct MI300X (192GB).
Every quantization on this machine
| Quant | Size | Speed | Fit |
|---|---|---|---|
| Q3_K_M | 10.9 GB | 277–415 tok/s | Runs great |
| Q4_K_M | 15.3 GB | 264–395 tok/s | Runs great |
| Q5_K_M | 18.0 GB | 256–384 tok/s | Runs great |
| Q6_K | 20.8 GB | 249–373 tok/s | Runs great |
| Q8_0 | 26.8 GB | 235–352 tok/s | Runs great |
| FP16 | 50.5 GB | 192–287 tok/s | Runs great |
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