Can I run this LLM?
Can a AMD Instinct MI355X (288GB) run Gemma 4 26B-A4B (MoE)?
Gemma · Apache 2.0 · estimated for a 288.0 GB machine at 4K context.
Yes — it runs great.
Best fit: Gemma 4 26B-A4B (MoE) at FP16 · 50.5 GB · 242–363 tok/s on a AMD Instinct MI355X (288GB).
Every quantization on this machine
| Quant | Size | Speed | Fit |
|---|---|---|---|
| Q3_K_M | 12.7 GB | 321–481 tok/s | Runs great |
| Q4_K_M | 17.0 GB | 310–465 tok/s | Runs great |
| Q5_K_M | 21.2 GB | 299–449 tok/s | Runs great |
| Q6_K | 23.2 GB | 294–442 tok/s | Runs great |
| Q8_0 | 26.9 GB | 286–429 tok/s | Runs great |
| FP16 | 50.5 GB | 242–363 tok/s | Runs great |
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